ARC Centre of Excellence in Synthetic Biology

Synthetic Biology


13, Mar 2024

Cauldron tech approval a boost for biomanufacturing

Industry partner Cauldron has just received approval from the gene technology regulator to produce animal proteins using microbes in batches of up to 10,000 litres.

The approval of its proprietary hyper-fermentation technology is being hailed as a demonstration of the readiness of Australia’s scientific ecosystem to lead biomanufacturing globally.

The Office of Gene Technology Regulator, part of the Australian Government’s Department of Health and Aged Care, found there was negligible risk with the technology which will be used with Pichia pastoris yeast to produce dairy, egg and spider-silk proteins.

‘This approval signals the establishment of a new, high growth industry for Australia, abounding with opportunities for ingredient production for domestic and export markets, advanced manufacturing, and regional development,’ says Cauldron CEO and Co Founder, Michele Stansfield.

‘It gives Cauldron the confidence to rapidly erect fermentation facilities that achieve significantly lower cost of goods at a fraction of the capital expenditure.’

Centre Director, Distinguished Professor Ian Paulsen, has welcomed the news, saying it is a significant step for the precision fermentation sector in Australia.

‘Australia has a world leading regulatory regime in OGTR and it’s great for the growing bioeconomy in Australia that they have given the tick of approval for Cauldron to proceed with large-scale biomanufacturing,’ he says.

Ms Stanfield says Cauldron is the first company in Australia to hold such a licence at the 10,000-litre scale ‘which unlocks production that all of our local synbio tech companies need to scale.’

Before companies can commercialise products using ingredients produced by Cauldron, food safety approval is required via Food Standards Australia New Zealand (FSANZ).

Photo: Provided